Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM131865'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM131865 (US8835444, 2.14) Show SMILES Cc1cnn(C[C@H]2CC[C@@H](CC2)NC(=O)c2cc(ccc2Cl)C(F)(F)F)c1C |r,wU:6.5,wD:9.12,(8.38,-1.42,;7.61,-.09,;8.52,1.15,;7.61,2.4,;6.15,1.93,;4.82,2.69,;3.48,1.93,;3.48,.38,;2.15,-.38,;.82,.38,;.82,1.93,;2.15,2.69,;-.52,-.38,;-1.85,.38,;-1.85,1.93,;-3.19,-.38,;-4.52,.38,;-5.85,-.38,;-5.85,-1.93,;-4.52,-2.69,;-3.19,-1.93,;-1.85,-2.69,;-7.19,.38,;-8.52,-.38,;-7.19,1.93,;-8.52,1.15,;6.15,.38,;4.82,-.38,)| Show InChI InChI=1S/C20H23ClF3N3O/c1-12-10-25-27(13(12)2)11-14-3-6-16(7-4-14)26-19(28)17-9-15(20(22,23)24)5-8-18(17)21/h5,8-10,14,16H,3-4,6-7,11H2,1-2H3,(H,26,28)/t14-,16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	214	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...				US Patent US8835444 (2014) BindingDB Entry DOI: 10.7270/Q28K77ST
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