Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM131879'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM131879 (US8835444, 5.17) Show SMILES Cc1cnn(C[C@H]2CC[C@@H](CC2)NC(=O)c2cc(ccc2Cl)C(F)(F)F)c1 |r,wU:6.5,wD:9.12,(8.73,-.94,;7.96,.39,;8.43,1.86,;7.19,2.76,;5.94,1.86,;4.61,2.63,;3.27,1.86,;3.27,.32,;1.94,-.45,;.61,.32,;.61,1.86,;1.94,2.63,;-.73,-.45,;-2.06,.32,;-2.06,1.86,;-3.39,-.45,;-4.73,.32,;-6.06,-.45,;-6.06,-1.99,;-4.73,-2.76,;-3.39,-1.99,;-2.06,-2.76,;-7.39,.32,;-7.39,1.86,;-8.73,-.45,;-8.73,1.09,;6.42,.39,)| Show InChI InChI=1S/C19H21ClF3N3O/c1-12-9-24-26(10-12)11-13-2-5-15(6-3-13)25-18(27)16-8-14(19(21,22)23)4-7-17(16)20/h4,7-10,13,15H,2-3,5-6,11H2,1H3,(H,25,27)/t13-,15-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...				US Patent US8835444 (2014) BindingDB Entry DOI: 10.7270/Q28K77ST
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