Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM29474'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM29474 (Pyrazolo[1,5-a]-1,3,5-triazine, 12-43) Show SMILES CCN(CC)c1nc(C)nc2c(c(C)nn12)-c1ccc(OC)c(C)c1C |(.35,9.67,;-.08,8.19,;-1.57,7.83,;-2.61,8.96,;-2.15,10.43,;-2.07,6.37,;-3.58,6.06,;-4.07,4.61,;-5.58,4.3,;-3.05,3.45,;-1.54,3.75,;-.31,2.83,;.95,3.72,;2.41,3.23,;.49,5.19,;-1.05,5.21,;-.33,1.29,;-1.66,.52,;-1.66,-1.02,;-.33,-1.79,;-.33,-3.33,;1.01,-4.1,;1.01,-1.02,;2.34,-1.79,;1.01,.52,;2.34,1.29,)| Show InChI InChI=1S/C20H27N5O/c1-8-24(9-2)20-22-15(6)21-19-18(14(5)23-25(19)20)16-10-11-17(26-7)13(4)12(16)3/h10-11H,8-9H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38.6	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company					Assay Description Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...				J Med Chem 52: 3073-83 (2009) Article DOI: 10.1021/jm9000242 BindingDB Entry DOI: 10.7270/Q23R0R6X
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