Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50074495'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074495 (CHEMBL355049 | [3-(2-Bromo-4-isopropyl-phenyl)-2,5...) Show SMILES CCCCN(CC)c1cc(C)nc2n(c(C)nc12)-c1ccc(cc1Br)C(C)C |(12.66,1.93,;12.66,.37,;11.33,-.4,;11.33,-1.94,;10,-2.71,;8.67,-1.94,;7.32,-2.71,;10,-4.25,;8.67,-5.02,;8.67,-6.55,;7.32,-7.34,;10,-7.32,;11.33,-6.55,;12.79,-7.02,;13.68,-5.79,;15.22,-5.8,;12.79,-4.54,;11.33,-5.02,;13.42,-8.43,;12.51,-9.68,;13.14,-11.09,;14.66,-11.25,;15.57,-10,;14.94,-8.6,;15.85,-7.35,;15.29,-12.67,;16.82,-12.85,;14.38,-13.92,)| Show InChI InChI=1S/C23H31BrN4/c1-7-9-12-27(8-2)21-13-16(5)25-23-22(21)26-17(6)28(23)20-11-10-18(15(3)4)14-19(20)24/h10-11,13-15H,7-9,12H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair