Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50074527'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074527 (CHEMBL169641 | [3-(2-Bromo-4-isopropyl-phenyl)-2,5...) Show SMILES COCCN(CCOC)c1cc(C)nc2n(c(C)nc12)-c1ccc(cc1Br)C(C)C |(13.97,1.76,;13.97,.21,;12.64,-.56,;12.64,-2.11,;11.31,-2.87,;9.98,-2.11,;8.65,-2.87,;7.3,-2.11,;5.97,-2.87,;11.31,-4.41,;9.98,-5.18,;9.98,-6.72,;8.63,-7.5,;11.31,-7.49,;12.64,-6.72,;14.11,-7.19,;15.01,-5.95,;16.55,-5.97,;14.11,-4.71,;12.64,-5.18,;14.74,-8.6,;13.83,-9.84,;14.46,-11.26,;15.99,-11.42,;16.9,-10.17,;16.27,-8.76,;17.18,-7.51,;16.6,-12.84,;15.69,-14.08,;18.14,-13.01,)| Show InChI InChI=1S/C23H31BrN4O2/c1-15(2)18-7-8-20(19(24)14-18)28-17(4)26-22-21(13-16(3)25-23(22)28)27(9-11-29-5)10-12-30-6/h7-8,13-15H,9-12H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
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