Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50417505'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50417505 (CHEMBL1287965) Show SMILES COc1ccc(-c2c(C)nn3c(NC4(CCC4)c4nc(C)no4)cc(C)nc23)c(C)c1 |(23.57,-41.97,;22.03,-41.99,;21.24,-40.66,;19.7,-40.67,;18.92,-39.37,;19.67,-38.02,;18.88,-36.7,;19.78,-35.46,;21.32,-35.45,;18.87,-34.21,;17.42,-34.69,;16.08,-33.93,;16.08,-32.38,;14.74,-31.62,;13.68,-30.52,;14.78,-29.45,;15.84,-30.55,;13.51,-32.56,;12.04,-32.11,;11.17,-33.36,;9.63,-33.4,;12.09,-34.59,;13.55,-34.1,;14.74,-34.7,;14.75,-36.24,;13.42,-37.02,;16.09,-37,;17.42,-36.23,;21.21,-38,;21.96,-36.65,;22,-39.33,)| Show InChI InChI=1S/C23H26N6O2/c1-13-11-17(30-5)7-8-18(13)20-15(3)27-29-19(12-14(2)24-21(20)29)26-23(9-6-10-23)22-25-16(4)28-31-22/h7-8,11-12,26H,6,9-10H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CRF1 receptor				Bioorg Med Chem Lett 20: 7259-64 (2010) Article DOI: 10.1016/j.bmcl.2010.10.095 BindingDB Entry DOI: 10.7270/Q2736S5V
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