Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50417507'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50417507 (CHEMBL1287996) Show SMILES CCC(Nc1cc(C)nc2c(c(C)nn12)-c1ccc(OC)cc1C)c1nnc(C)o1 |(13.26,-29.56,;14.57,-30.33,;14.57,-31.87,;15.9,-32.65,;15.88,-34.19,;14.52,-34.95,;14.51,-36.49,;13.17,-37.25,;15.84,-37.27,;17.18,-36.52,;18.64,-37.01,;19.56,-35.78,;21.1,-35.8,;18.67,-34.52,;17.2,-34.98,;19.41,-38.34,;18.64,-39.68,;19.4,-41,;20.94,-41.01,;21.71,-42.34,;23.26,-42.35,;21.72,-39.69,;20.95,-38.34,;21.72,-37.01,;13.33,-32.79,;13.35,-34.33,;11.88,-34.8,;10.97,-33.56,;9.43,-33.57,;11.86,-32.32,)| Show InChI InChI=1S/C22H26N6O2/c1-7-18(22-26-25-15(5)30-22)24-19-11-13(3)23-21-20(14(4)27-28(19)21)17-9-8-16(29-6)10-12(17)2/h8-11,18,24H,7H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CRF1 receptor				Bioorg Med Chem Lett 20: 7259-64 (2010) Article DOI: 10.1016/j.bmcl.2010.10.095 BindingDB Entry DOI: 10.7270/Q2736S5V
					More data for this Ligand-Target Pair