Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50417509'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50417509 (CHEMBL1288026) Show SMILES COc1ccc(-c2c(C)nn3c(NC(C)Cc4noc(C)n4)cc(C)nc23)c(C)c1 |(24.48,-40.44,;22.94,-40.39,;22.2,-39.04,;20.66,-39,;19.93,-37.66,;20.73,-36.34,;19.99,-34.99,;20.87,-33.74,;22.41,-33.71,;19.94,-32.51,;18.49,-33,;17.15,-32.26,;17.12,-30.72,;15.77,-29.97,;15.72,-28.44,;14.41,-30.69,;13.19,-29.76,;13.22,-28.24,;11.77,-27.73,;10.84,-28.95,;9.31,-28.92,;11.72,-30.21,;15.81,-33.06,;15.85,-34.6,;14.53,-35.39,;17.2,-35.34,;18.52,-34.54,;22.27,-36.38,;23.07,-35.06,;23,-37.74,)| Show InChI InChI=1S/C22H26N6O2/c1-12-9-17(29-6)7-8-18(12)21-15(4)26-28-20(11-14(3)24-22(21)28)23-13(2)10-19-25-16(5)30-27-19/h7-9,11,13,23H,10H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	79.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CRF1 receptor				Bioorg Med Chem Lett 20: 7259-64 (2010) Article DOI: 10.1016/j.bmcl.2010.10.095 BindingDB Entry DOI: 10.7270/Q2736S5V
					More data for this Ligand-Target Pair