Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50420911'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50420911 (CHEMBL2087557) Show SMILES CCc1nn2c(cccc2c1N(CCOC)CC1CC1)-c1c(C)cc(C)cc1OC |(-4.74,1.26,;-3.99,-.08,;-2.45,-.09,;-1.55,-1.35,;-.08,-.88,;1.25,-1.66,;2.59,-.9,;2.6,.64,;1.27,1.42,;-.07,.66,;-1.53,1.15,;-1.99,2.61,;-.96,3.75,;-1.5,5.19,;-.52,6.38,;-1.06,7.82,;-3.5,2.95,;-4.04,4.39,;-5.23,5.37,;-3.79,5.91,;1.23,-3.2,;-.11,-3.96,;-1.43,-3.18,;-.12,-5.5,;1.21,-6.28,;1.2,-7.82,;2.55,-5.52,;2.56,-3.98,;3.9,-3.22,;5.23,-4,)| Show InChI InChI=1S/C25H33N3O2/c1-6-20-25(27(12-13-29-4)16-19-10-11-19)22-9-7-8-21(28(22)26-20)24-18(3)14-17(2)15-23(24)30-5/h7-9,14-15,19H,6,10-13,16H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counter				J Med Chem 55: 5255-69 (2012) Article DOI: 10.1021/jm300259r BindingDB Entry DOI: 10.7270/Q29P32XC
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