Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50420917'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50420917 (CHEMBL2087563) Show SMILES CCc1nn2c(cccc2c1N(CC1CC1)CC1CCOCC1)-c1c(C)cc(OC)cc1OC |(-3.66,-1.15,;-2.89,.19,;-1.35,.17,;-.46,-1.08,;1.01,-.62,;2.34,-1.4,;3.68,-.64,;3.69,.9,;2.37,1.68,;1.03,.92,;-.44,1.41,;-.9,2.88,;-2.4,3.21,;-3.5,2.13,;-4.99,1.75,;-3.91,.65,;.14,4.01,;-.4,5.46,;.58,6.65,;.05,8.09,;-1.47,8.34,;-2.45,7.15,;-1.91,5.71,;2.32,-2.94,;3.65,-3.72,;4.99,-2.97,;3.64,-5.26,;2.3,-6.02,;2.28,-7.56,;3.61,-8.34,;.97,-5.24,;.98,-3.7,;-.34,-2.92,;-1.68,-3.67,)| Show InChI InChI=1S/C28H37N3O3/c1-5-23-28(30(17-20-9-10-20)18-21-11-13-34-14-12-21)25-8-6-7-24(31(25)29-23)27-19(2)15-22(32-3)16-26(27)33-4/h6-8,15-16,20-21H,5,9-14,17-18H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counter				J Med Chem 55: 5255-69 (2012) Article DOI: 10.1021/jm300259r BindingDB Entry DOI: 10.7270/Q29P32XC
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