Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50420929'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50420929 (CHEMBL2087794) Show SMILES COCc1cc(OC)c(c(OC)c1)-c1cccc2c(N(CC3CC3)CC3CCOCC3)c(nn12)C#N |(2.63,-8.83,;2.66,-7.29,;1.35,-6.49,;1.38,-4.95,;2.73,-4.21,;2.76,-2.67,;4.11,-1.92,;5.43,-2.72,;1.44,-1.87,;.09,-2.61,;-1.23,-1.81,;-2.57,-2.56,;.06,-4.15,;1.47,-.33,;2.82,.41,;2.85,1.95,;1.54,2.75,;.19,2.01,;-1.27,2.51,;-1.71,3.99,;-.66,5.11,;.86,4.84,;2.31,5.36,;2.03,3.84,;-3.21,4.34,;-3.58,5.83,;-5.06,6.26,;-5.43,7.76,;-4.31,8.83,;-2.84,8.4,;-2.47,6.9,;-2.2,1.29,;-1.32,.02,;.16,.47,;-3.74,1.32,;-5.28,1.35,)| Show InChI InChI=1S/C28H34N4O4/c1-33-18-21-13-25(34-2)27(26(14-21)35-3)23-5-4-6-24-28(22(15-29)30-32(23)24)31(16-19-7-8-19)17-20-9-11-36-12-10-20/h4-6,13-14,19-20H,7-12,16-18H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated cAMP accumulation after 30 mins by fluo...				J Med Chem 55: 5255-69 (2012) Article DOI: 10.1021/jm300259r BindingDB Entry DOI: 10.7270/Q29P32XC
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50420929 (CHEMBL2087794) Show SMILES COCc1cc(OC)c(c(OC)c1)-c1cccc2c(N(CC3CC3)CC3CCOCC3)c(nn12)C#N |(2.63,-8.83,;2.66,-7.29,;1.35,-6.49,;1.38,-4.95,;2.73,-4.21,;2.76,-2.67,;4.11,-1.92,;5.43,-2.72,;1.44,-1.87,;.09,-2.61,;-1.23,-1.81,;-2.57,-2.56,;.06,-4.15,;1.47,-.33,;2.82,.41,;2.85,1.95,;1.54,2.75,;.19,2.01,;-1.27,2.51,;-1.71,3.99,;-.66,5.11,;.86,4.84,;2.31,5.36,;2.03,3.84,;-3.21,4.34,;-3.58,5.83,;-5.06,6.26,;-5.43,7.76,;-4.31,8.83,;-2.84,8.4,;-2.47,6.9,;-2.2,1.29,;-1.32,.02,;.16,.47,;-3.74,1.32,;-5.28,1.35,)| Show InChI InChI=1S/C28H34N4O4/c1-33-18-21-13-25(34-2)27(26(14-21)35-3)23-5-4-6-24-28(22(15-29)30-32(23)24)31(16-19-7-8-19)17-20-9-11-36-12-10-20/h4-6,13-14,19-20H,7-12,16-18H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counter				J Med Chem 55: 5255-69 (2012) Article DOI: 10.1021/jm300259r BindingDB Entry DOI: 10.7270/Q29P32XC
					More data for this Ligand-Target Pair