Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50420938'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50420938 (CHEMBL2087564) Show SMILES CCc1nn2c(cccc2c1N(CC1CC1)CC1CCOCC1)-c1c(OC)cc(OC)cc1OC |(-4.48,1.81,;-3.71,.48,;-2.17,.49,;-1.26,-.76,;.2,-.28,;1.54,-1.05,;2.87,-.27,;2.87,1.27,;1.53,2.03,;.2,1.26,;-1.27,1.73,;-1.74,3.2,;-.72,4.34,;.8,4.11,;2.24,4.66,;2,3.14,;-3.25,3.51,;-3.65,5,;-5.14,5.4,;-5.54,6.88,;-4.46,7.97,;-2.97,7.58,;-2.57,6.09,;1.54,-2.59,;2.88,-3.35,;4.21,-2.58,;5.54,-3.35,;2.88,-4.89,;1.55,-5.67,;1.55,-7.21,;2.89,-7.97,;.21,-4.9,;.21,-3.36,;-1.13,-2.59,;-2.46,-3.37,)| Show InChI InChI=1S/C28H37N3O4/c1-5-22-28(30(17-19-9-10-19)18-20-11-13-35-14-12-20)24-8-6-7-23(31(24)29-22)27-25(33-3)15-21(32-2)16-26(27)34-4/h6-8,15-16,19-20H,5,9-14,17-18H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counter				J Med Chem 55: 5255-69 (2012) Article DOI: 10.1021/jm300259r BindingDB Entry DOI: 10.7270/Q29P32XC
					More data for this Ligand-Target Pair