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Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-C/Cyclin-dependent kinase 19' and Ligand = 'BDBM350199'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-C/Cyclin-dependent kinase 19


(Homo sapiens (Human))		BDBM350199
PNG
(US10208056, Compound 31)
Show SMILES CC1(C)Oc2cnccc2-c2[nH]c(C(N)=O)c(c12)-c1ccccc1
Show InChI InChI=1S/C19H17N3O2/c1-19(2)15-14(11-6-4-3-5-7-11)17(18(20)23)22-16(15)12-8-9-21-10-13(12)24-19/h3-10,22H,1-2H3,(H2,20,23)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 107n/an/an/an/an/an/a



FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO)

US Patent


Assay Description
The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen). This is a kinase assay platform based on measuring the binding an...

US Patent US10208056 (2019)


BindingDB Entry DOI: 10.7270/Q2GB266B
More data for this
Ligand-Target Pair