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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-C' and Ligand = 'BDBM50189500'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-C


(Homo sapiens (Human))		BDBM50189500
PNG
(CHEMBL3827664)
Show SMILES Cn1cc(cn1)-c1ccc(cc1)-c1cnc(N)c2ccc(cc12)C(=O)NC1CC1
Show InChI InChI=1S/C23H21N5O/c1-28-13-17(11-26-28)14-2-4-15(5-3-14)21-12-25-22(24)19-9-6-16(10-20(19)21)23(29)27-18-7-8-18/h2-6,9-13,18H,7-8H2,1H3,(H2,24,25)(H,27,29)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 9.10n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Competitive binding affinity to full length His-tagged human recombinant CDK8/cyclin C expressed in baculovirus after 20 mins in presence of Alexa647...

ACS Med Chem Lett 7: 573-8 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00022
BindingDB Entry DOI: 10.7270/Q2N87CRB
More data for this
Ligand-Target Pair