Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-C (Homo sapiens (Human)) | BDBM50585694 (CHEMBL4878072) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of kinase tracer 236 binding to His tagged recombinant human CDK8/cyclin C incubated for 60 min FRET based LanthaScreen Eu-Kinase binding ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01951 BindingDB Entry DOI: 10.7270/Q2WD44G8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C (Homo sapiens (Human)) | BDBM50585694 (CHEMBL4878072) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to kinase tracer 236 binding to His tagged recombinant human CDK8/cyclinC assessed as dissociation constant by TR FRET based assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01951 BindingDB Entry DOI: 10.7270/Q2WD44G8 | |||||||||||
More data for this Ligand-Target Pair |