Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human)) | BDBM8891 (3-(6-Methoxy-3,4-dihydronaphthalen-2-yl)pyridine |...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.30 | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Saarland University | Assay Description The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro... | Pharmacol Rev 49: 2222-31 (2006) Article DOI: 10.1021/jm060055x BindingDB Entry DOI: 10.7270/Q2MW2FBS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human)) | BDBM8891 (3-(6-Methoxy-3,4-dihydronaphthalen-2-yl)pyridine |...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | 37 |
UNIVERSITAT DES SAARLANDES US Patent | Assay Description V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per... | US Patent US9271963 (2016) BindingDB Entry DOI: 10.7270/Q2445KBN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human)) | BDBM8891 (3-(6-Methoxy-3,4-dihydronaphthalen-2-yl)pyridine |...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Saarland University Curated by ChEMBL | Assay Description Inhibition of human CYP11B2 expressed in hamster V79 MZh cells | J Med Chem 51: 5064-74 (2008) Article DOI: 10.1021/jm800377h BindingDB Entry DOI: 10.7270/Q2Z89C75 | |||||||||||
More data for this Ligand-Target Pair |