BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Cytochrome P450 26A1' and Ligand = 'BDBM50158411'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cytochrome P450 26A1 (Homo sapiens (Human))	BDBM50158411 ((2E,4E,6E,8E)-9-(3-Imidazol-1-yl-2,6,6-trimethyl-c...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibition of ATRA-induced CYP26 in human T47D cells assessed as ATRA metabolism using [11.12-3H]-ATRA				J Med Chem 47: 6716-29 (2004) Article DOI: 10.1021/jm0401457 BindingDB Entry DOI: 10.7270/Q2K64HJV
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 26A1 (Homo sapiens (Human))	BDBM50158411 ((2E,4E,6E,8E)-9-(3-Imidazol-1-yl-2,6,6-trimethyl-c...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibition of ATRA-induced CYP26 in human MCF7 cells assessed ATRA as metabolism using [11.12-3H]-ATRA				J Med Chem 47: 6716-29 (2004) Article DOI: 10.1021/jm0401457 BindingDB Entry DOI: 10.7270/Q2K64HJV
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair