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Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50010059'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50010059
PNG
(2-{3-[4-(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazo...)
Show SMILES O=S1(=O)N=C(N2CCN(CCCN3c4cccc5cccc(c45)S3(=O)=O)CC2)c2ccccc12 |t:3|
Show InChI InChI=1S/C24H24N4O4S2/c29-33(30)21-10-2-1-8-19(21)24(25-33)27-16-14-26(15-17-27)12-5-13-28-20-9-3-6-18-7-4-11-22(23(18)20)34(28,31)32/h1-4,6-11H,5,12-17H2
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PC cid
PC sid
UniChem
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer

Curated by ChEMBL


Assay Description
The concentration required to inhibit [3H]spiperone binding to dopamine receptor D2 in rat brain membranes (in vitro)

J Med Chem 34: 2477-83 (1991)


BindingDB Entry DOI: 10.7270/Q2R78FT1
More data for this
Ligand-Target Pair