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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'D(4) dopamine receptor' and Ligand = 'BDBM50153257'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(4) dopamine receptor


(Homo sapiens (Human))		BDBM50153257
PNG
(CHEMBL185149 | N-(4-Bromo-3-methyl-phenyl)-2-[4-(2...)
Show SMILES Cc1cc(NC(=O)CN2CCN(CC2)c2ccccc2C#N)ccc1Br
Show InChI InChI=1S/C20H21BrN4O/c1-15-12-17(6-7-18(15)21)23-20(26)14-24-8-10-25(11-9-24)19-5-3-2-4-16(19)13-22/h2-7,12H,8-11,14H2,1H3,(H,23,26)
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Article
PubMed
n/an/an/an/a 96n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity was calculated in calcium flux assay using HEK-293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5

Bioorg Med Chem Lett 14: 5095-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.068
BindingDB Entry DOI: 10.7270/Q23X863Q
More data for this
Ligand-Target Pair