BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'D(4) dopamine receptor' and Ligand = 'BDBM50189842'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50189842 (2-[4-(4-chlorophenyl)piperazin-1-yl)methyl]imidazo...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cn3ccccc3n2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Chimie Th�rapeutique Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membrane				J Med Chem 49: 3938-47 (2006) Article DOI: 10.1021/jm060166w BindingDB Entry DOI: 10.7270/Q20G3KZ5
Laboratoire de Chimie Th�rapeutique Curated by ChEMBL					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50189842 (2-[4-(4-chlorophenyl)piperazin-1-yl)methyl]imidazo...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cn3ccccc3n2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University Curated by ChEMBL					Assay Description Agonist activity at dopamine D4 receptor (unknown origin)				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111569 BindingDB Entry DOI: 10.7270/Q2H41VXG
Palack£ University Curated by ChEMBL					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50189842 (2-[4-(4-chlorophenyl)piperazin-1-yl)methyl]imidazo...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cn3ccccc3n2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University Curated by ChEMBL					Assay Description Agonist activity at dopamine D4 receptor (unknown origin)				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.111569 BindingDB Entry DOI: 10.7270/Q2H41VXG
Palack£ University Curated by ChEMBL					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50189842 (2-[4-(4-chlorophenyl)piperazin-1-yl)methyl]imidazo...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cn3ccccc3n2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a
Laboratoire de Chimie Th�rapeutique Curated by ChEMBL					Assay Description Activity at human D4.2 receptor assessed as [3H]thymidine incorporation in CHO 10001 cells by mitogenesis assay				J Med Chem 49: 3938-47 (2006) Article DOI: 10.1021/jm060166w BindingDB Entry DOI: 10.7270/Q20G3KZ5
Laboratoire de Chimie Th�rapeutique Curated by ChEMBL					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50189842 (2-[4-(4-chlorophenyl)piperazin-1-yl)methyl]imidazo...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cn3ccccc3n2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.60	n/a	n/a	n/a	n/a
Laboratoire de Chimie Th�rapeutique Curated by ChEMBL					Assay Description Activity at human D4.4 receptor expressed in CHOK1 cells assessed as stimulation of [35S]GTP-gammaS binding				J Med Chem 49: 3938-47 (2006) Article DOI: 10.1021/jm060166w BindingDB Entry DOI: 10.7270/Q20G3KZ5
Laboratoire de Chimie Th�rapeutique Curated by ChEMBL					More data for this Ligand-Target Pair