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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'DCN1-like protein 1' and Ligand = 'BDBM50584167'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DCN1-like protein 1


(Homo sapiens)
BDBM50584167
PNG
(CHEMBL5085822)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(SCc2ccc(Cl)cc2)nc(Sc2nnnn2C)c1C#N
PDB

UniProtKB/SwissProt

GoogleScholar
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MCE
PC cid
PC sid
UniChem
Article
PubMed
8.30n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity to DCN1 (unknown origin) assessed as inhibitory constant


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01207
BindingDB Entry DOI: 10.7270/Q2JD51NJ
More data for this
Ligand-Target Pair
DCN1-like protein 1


(Homo sapiens)
BDBM50584167
PNG
(CHEMBL5085822)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(SCc2ccc(Cl)cc2)nc(Sc2nnnn2C)c1C#N
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.60n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assay


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01207
BindingDB Entry DOI: 10.7270/Q2JD51NJ
More data for this
Ligand-Target Pair
DCN1-like protein 1


(Homo sapiens)
BDBM50584167
PNG
(CHEMBL5085822)
Show SMILES COc1cc(cc(OC)c1OC)-c1nc(SCc2ccc(Cl)cc2)nc(Sc2nnnn2C)c1C#N
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 26n/an/an/an/an/a


TBA

Assay Description
Binding affinity to extracellular DCN1 (unknown origin) assessed as dissociation constant incubated for upto 180 secs by label-free biolayer interfer...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01207
BindingDB Entry DOI: 10.7270/Q2JD51NJ
More data for this
Ligand-Target Pair