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Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit B' and Ligand = 'BDBM50378420'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA gyrase subunit B


(Streptococcus pneumoniae)		BDBM50378420
PNG
(CHEMBL565750)
Show SMILES CCNC(=O)Nc1cn2c(cc(cc2n1)-c1ccn(CC)c(=O)c1)-c1ncc(C)cn1
Show InChI InChI=1S/C22H23N7O2/c1-4-23-22(31)27-18-13-29-17(21-24-11-14(3)12-25-21)8-16(9-19(29)26-18)15-6-7-28(5-2)20(30)10-15/h6-13H,4-5H2,1-3H3,(H2,23,27,31)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 51n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assay

Bioorg Med Chem Lett 19: 5302-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.141
BindingDB Entry DOI: 10.7270/Q23X87KD
More data for this
Ligand-Target Pair