Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA ligase A (Mycobacterium tuberculosis) | BDBM22982 (Glycosyl Ureides, 3b | ethyl 3-[(3aS,6R,6aS)-6-(be...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
Central Drug Research Institute | Assay Description All assays have been carried out using procedures previously described by our group (Srivastava et al., 2005a; 2005b; 2007) | Medicinal Chemistry Research 17: 189-198 (2008) BindingDB Entry DOI: 10.7270/Q2PG1QB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase A (Mycobacterium tuberculosis) | BDBM22982 (Glycosyl Ureides, 3b | ethyl 3-[(3aS,6R,6aS)-6-(be...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | 8.0 | 25 |
India Central Drug Research Institute | Assay Description The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were... | J Biol Chem 280: 30273-81 (2005) Article DOI: 10.1074/jbc.M503780200 BindingDB Entry DOI: 10.7270/Q2SX6BGR | |||||||||||
More data for this Ligand-Target Pair |