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Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA ligase A' and Ligand = 'BDBM22983'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA ligase A


(Mycobacterium tuberculosis)		BDBM22983
PNG
(ethyl 3-[({3-[({1-[(3aR,6S,6aR)-6-(benzyloxy)-2,2-...)
Show SMILES CCOC(=O)CC(NC(=O)Nc1cccc(NC(=O)NC(CC(=O)OCC)C2O[C@H]3OC(C)(C)O[C@H]3[C@@H]2OCc2ccccc2)c1)C1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1OCc1ccccc1 |r|
Show InChI InChI=1S/C46H58N4O14/c1-7-55-33(51)23-31(35-37(57-25-27-16-11-9-12-17-27)39-41(59-35)63-45(3,4)61-39)49-43(53)47-29-20-15-21-30(22-29)48-44(54)50-32(24-34(52)56-8-2)36-38(58-26-28-18-13-10-14-19-28)40-42(60-36)64-46(5,6)62-40/h9-22,31-32,35-42H,7-8,23-26H2,1-6H3,(H2,47,49,53)(H2,48,50,54)/t31?,32?,35?,36?,37-,38+,39+,40-,41+,42-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.77E+4n/an/an/an/a8.025



India Central Drug Research Institute



Assay Description
The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were...

J Biol Chem 280: 30273-81 (2005)


Article DOI: 10.1074/jbc.M503780200
BindingDB Entry DOI: 10.7270/Q2SX6BGR
More data for this
Ligand-Target Pair