Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 2-alpha/2-beta' and Ligand = 'BDBM50212604'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human))	BDBM50212604 (CHEMBL422265) Show SMILES CN\N=c1/ccn(C2CC2)c2c(F)c(c(F)cc12)-c1cc(C)nc(C)c1 Show InChI InChI=1S/C20H20F2N4/c1-11-8-13(9-12(2)24-11)18-16(21)10-15-17(25-23-3)6-7-26(14-4-5-14)20(15)19(18)22/h6-10,14,23H,4-5H2,1-3H3/b25-17+	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents		n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.				Citation and Details BindingDB Entry DOI: 10.7270/Q2R49SXV
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