BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with Target = 'DNA-dependent protein kinase catalytic subunit' and Ligand = 'BDBM50098126'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50098126 (2-(morpholin-4-yl)-benzo[h]chromen-4-one \| 2-Morph...) Show SMILES O=c1cc(oc2c3ccccc3ccc12)N1CCOCC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
University of Newcastle Curated by ChEMBL					Assay Description In vitro inhibition of DNA-dependent protein kinase(DNA-PK) from HeLa (human carcinoma) cells.				Bioorg Med Chem Lett 13: 3083-6 (2003) BindingDB Entry DOI: 10.7270/Q2WS8SP4
University of Newcastle Curated by ChEMBL					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50098126 (2-(morpholin-4-yl)-benzo[h]chromen-4-one \| 2-Morph...) Show SMILES O=c1cc(oc2c3ccccc3ccc12)N1CCOCC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
The University Curated by ChEMBL					Assay Description Inhibition of DNA dependent protein kinase isolated from HeLa cells				J Med Chem 48: 569-85 (2005) Article DOI: 10.1021/jm049526a BindingDB Entry DOI: 10.7270/Q2BK1BV9
The University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50098126 (2-(morpholin-4-yl)-benzo[h]chromen-4-one \| 2-Morph...) Show SMILES O=c1cc(oc2c3ccccc3ccc12)N1CCOCC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against DNA-dependent protein kinase (DNA-PK)				Bioorg Med Chem Lett 14: 6083-7 (2004) Article DOI: 10.1016/j.bmcl.2004.09.060 BindingDB Entry DOI: 10.7270/Q22J6BBN
University of Newcastle Curated by ChEMBL					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50098126 (2-(morpholin-4-yl)-benzo[h]chromen-4-one \| 2-Morph...) Show SMILES O=c1cc(oc2c3ccccc3ccc12)N1CCOCC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of DNA-PK				Proc Natl Acad Sci USA 104: 20523-8 (2007) Checked by Author Article DOI: 10.1073/pnas.0708800104 BindingDB Entry DOI: 10.7270/Q2DB82RH
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50098126 (2-(morpholin-4-yl)-benzo[h]chromen-4-one \| 2-Morph...) Show SMILES O=c1cc(oc2c3ccccc3ccc12)N1CCOCC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
School of Natural Sciences--Chemistry Curated by ChEMBL					Assay Description Inhibitory activity against DNA-dependent protein kinase receptor				J Med Chem 48: 7829-46 (2005) Article DOI: 10.1021/jm050444b BindingDB Entry DOI: 10.7270/Q2Z31Z60
School of Natural Sciences--Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50098126 (2-(morpholin-4-yl)-benzo[h]chromen-4-one \| 2-Morph...) Show SMILES O=c1cc(oc2c3ccccc3ccc12)N1CCOCC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals (Europe) Ltd. Curated by ChEMBL					Assay Description Inhibition of DNAPK after 2 hrs by radiometric phosphate incorporation assay				J Med Chem 54: 2320-30 (2011) Article DOI: 10.1021/jm101488z BindingDB Entry DOI: 10.7270/Q2WS8TK6
Vertex Pharmaceuticals (Europe) Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50098126 (2-(morpholin-4-yl)-benzo[h]chromen-4-one \| 2-Morph...) Show SMILES O=c1cc(oc2c3ccccc3ccc12)N1CCOCC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital Hradec Kralove Curated by ChEMBL					Assay Description Inhibition of DNA-PK purified from human HeLa nuclear extracts				J Med Chem 58: 41-71 (2015) Article DOI: 10.1021/jm501026z BindingDB Entry DOI: 10.7270/Q2P84DJ7
University Hospital Hradec Kralove Curated by ChEMBL					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50098126 (2-(morpholin-4-yl)-benzo[h]chromen-4-one \| 2-Morph...) Show SMILES O=c1cc(oc2c3ccccc3ccc12)N1CCOCC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of DNA-PK				Bioorg Med Chem 19: 3983-94 (2011) Article DOI: 10.1016/j.bmc.2011.05.032 BindingDB Entry DOI: 10.7270/Q20Z73M7
La Trobe University Curated by ChEMBL					More data for this Ligand-Target Pair