BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = 'Delta-type opioid receptor' and Ligand = 'BDBM50297170'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50297170 (7-(2'-spiroindanyl)oxymorphone \| 7-(Spiroindano)Ox...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Antagonism against bradykinin receptor B2 in guinea pig ileal tissue				J Med Chem 36: 2572-4 (1993) BindingDB Entry DOI: 10.7270/Q27H1K62
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50297170 (7-(2'-spiroindanyl)oxymorphone \| 7-(Spiroindano)Ox...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description The compound tested for agonistic activity against Opioid receptor delta 1 using [3H]- NT1 as the radioligand.				J Med Chem 40: 1720-5 (1997) Article DOI: 10.1021/jm9700880 BindingDB Entry DOI: 10.7270/Q2FB53M9
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (MOUSE)	BDBM50297170 (7-(2'-spiroindanyl)oxymorphone \| 7-(Spiroindano)Ox...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of [3H]-NTI binding to Opioid receptor delta 1 from mouse brain membranes.				J Med Chem 40: 3064-70 (1997) Article DOI: 10.1021/jm970283e BindingDB Entry DOI: 10.7270/Q27D2T7R
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50297170 (7-(2'-spiroindanyl)oxymorphone \| 7-(Spiroindano)Ox...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Selective binding affinity against Opioid receptor delta 2, using [3H]DSLET as radioligand				J Med Chem 36: 2572-4 (1993) BindingDB Entry DOI: 10.7270/Q27H1K62
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (MOUSE)	BDBM50297170 (7-(2'-spiroindanyl)oxymorphone \| 7-(Spiroindano)Ox...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of [3H]- diprenorphine from delta receptor expressed in HEK 293 cells				J Med Chem 44: 857-62 (2001) BindingDB Entry DOI: 10.7270/Q27H1K9D
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (MOUSE)	BDBM50297170 (7-(2'-spiroindanyl)oxymorphone \| 7-(Spiroindano)Ox...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	46.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of [3H]- diprenorphine from delta-W284E-receptor expressed in HEK 293 cells				J Med Chem 44: 857-62 (2001) BindingDB Entry DOI: 10.7270/Q27H1K9D
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair