Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50399694'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50399694 (CHEMBL2178934) Show SMILES NC(=O)c1cncc(n1)-c1ccc(cc1)[C@H]1CC[C@H](CCO)CC1 |r,wU:15.16,wD:18.20,(57.84,-21.32,;59.18,-20.56,;59.18,-19.02,;60.51,-21.33,;60.51,-22.87,;61.85,-23.64,;63.18,-22.87,;63.18,-21.33,;61.84,-20.56,;64.51,-20.56,;65.84,-21.34,;67.18,-20.56,;67.17,-19.01,;65.84,-18.25,;64.51,-19.02,;68.51,-18.24,;68.5,-16.71,;69.83,-15.93,;71.17,-16.7,;72.5,-15.93,;73.84,-16.7,;75.17,-15.93,;71.17,-18.24,;69.84,-19.01,)| Show InChI InChI=1S/C19H23N3O2/c20-19(24)18-12-21-11-17(22-18)16-7-5-15(6-8-16)14-3-1-13(2-4-14)9-10-23/h5-8,11-14,23H,1-4,9-10H2,(H2,20,24)/t13-,14-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillography				J Med Chem 55: 10610-29 (2012) Article DOI: 10.1021/jm301296t BindingDB Entry DOI: 10.7270/Q2XD12T3
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