Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50438744'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50438744 (CHEMBL2414700) Show SMILES NC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)N1CCOc2ncnc(N)c2C1=O |r,wU:7.10,wD:4.3,(38.2,-37.65,;37.22,-38.85,;37.76,-40.29,;35.69,-38.61,;34.72,-39.81,;33.22,-39.6,;32.26,-40.78,;32.8,-42.2,;34.3,-42.45,;35.27,-41.26,;31.81,-43.41,;32.37,-44.88,;31.41,-46.06,;29.91,-45.81,;29.36,-44.39,;30.32,-43.21,;28.92,-47.03,;29.6,-48.43,;28.93,-49.82,;27.42,-50.17,;26.22,-49.19,;24.88,-49.96,;23.54,-49.18,;23.55,-47.64,;24.88,-46.88,;24.89,-45.33,;26.22,-47.65,;27.43,-46.69,;27.09,-45.19,)| Show InChI InChI=1S/C21H25N5O3/c22-17(27)11-13-1-3-14(4-2-13)15-5-7-16(8-6-15)26-9-10-29-20-18(21(26)28)19(23)24-12-25-20/h5-8,12-14H,1-4,9-11H2,(H2,22,27)(H2,23,24,25)/t13-,14-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human full length DGAT-1 expressed in insect sf9 cells using [14C]decanoylCoA as substrate after 1.5 hrs by scintillation spectrometry				Bioorg Med Chem 21: 5081-97 (2013) Article DOI: 10.1016/j.bmc.2013.06.045 BindingDB Entry DOI: 10.7270/Q26111RG
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50438744 (CHEMBL2414700) Show SMILES NC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)N1CCOc2ncnc(N)c2C1=O |r,wU:7.10,wD:4.3,(38.2,-37.65,;37.22,-38.85,;37.76,-40.29,;35.69,-38.61,;34.72,-39.81,;33.22,-39.6,;32.26,-40.78,;32.8,-42.2,;34.3,-42.45,;35.27,-41.26,;31.81,-43.41,;32.37,-44.88,;31.41,-46.06,;29.91,-45.81,;29.36,-44.39,;30.32,-43.21,;28.92,-47.03,;29.6,-48.43,;28.93,-49.82,;27.42,-50.17,;26.22,-49.19,;24.88,-49.96,;23.54,-49.18,;23.55,-47.64,;24.88,-46.88,;24.89,-45.33,;26.22,-47.65,;27.43,-46.69,;27.09,-45.19,)| Show InChI InChI=1S/C21H25N5O3/c22-17(27)11-13-1-3-14(4-2-13)15-5-7-16(8-6-15)26-9-10-29-20-18(21(26)28)19(23)24-12-25-20/h5-8,12-14H,1-4,9-11H2,(H2,22,27)(H2,23,24,25)/t13-,14-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of DGAT-1-mediated triglyceride synthesis in human HT-29 cells using [3H]-glycerol as substrate incubated for 1 hr prior to substrate addi...				Bioorg Med Chem 21: 5081-97 (2013) Article DOI: 10.1016/j.bmc.2013.06.045 BindingDB Entry DOI: 10.7270/Q26111RG
					More data for this Ligand-Target Pair