Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50135135'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Escherichia coli)	BDBM50135135 (6-(Naphthalen-2-ylaminomethyl)-pyrido[2,3-d]pyrimi...) Show SMILES Nc1nc(N)c2cc(CNc3ccc4ccccc4c3)cnc2n1 Show InChI InChI=1S/C18H16N6/c19-16-15-7-11(10-22-17(15)24-18(20)23-16)9-21-14-6-5-12-3-1-2-4-13(12)8-14/h1-8,10,21H,9H2,(H4,19,20,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of dihydrofolate reductase from toxoplasma gondii.				J Med Chem 46: 5074-82 (2003) Article DOI: 10.1021/jm030312n BindingDB Entry DOI: 10.7270/Q2J38RZ9
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Escherichia coli)	BDBM50135135 (6-(Naphthalen-2-ylaminomethyl)-pyrido[2,3-d]pyrimi...) Show SMILES Nc1nc(N)c2cc(CNc3ccc4ccccc4c3)cnc2n1 Show InChI InChI=1S/C18H16N6/c19-16-15-7-11(10-22-17(15)24-18(20)23-16)9-21-14-6-5-12-3-1-2-4-13(12)8-14/h1-8,10,21H,9H2,(H4,19,20,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of dihydrofolate reductase from pneumocystis carinii.				J Med Chem 46: 5074-82 (2003) Article DOI: 10.1021/jm030312n BindingDB Entry DOI: 10.7270/Q2J38RZ9
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Rattus norvegicus (rat))	BDBM50135135 (6-(Naphthalen-2-ylaminomethyl)-pyrido[2,3-d]pyrimi...) Show SMILES Nc1nc(N)c2cc(CNc3ccc4ccccc4c3)cnc2n1 Show InChI InChI=1S/C18H16N6/c19-16-15-7-11(10-22-17(15)24-18(20)23-16)9-21-14-6-5-12-3-1-2-4-13(12)8-14/h1-8,10,21H,9H2,(H4,19,20,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of dihydrofolate reductase from rat liver.				J Med Chem 46: 5074-82 (2003) Article DOI: 10.1021/jm030312n BindingDB Entry DOI: 10.7270/Q2J38RZ9
					More data for this Ligand-Target Pair