Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50316121 (CHEMBL1089229 | N-(3-Benzyl-2-cinnamylthio-4-oxo-3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University Curated by ChEMBL | Assay Description Inhibition of human DHFR after 2 mins | Bioorg Med Chem 18: 2849-63 (2010) Article DOI: 10.1016/j.bmc.2010.03.019 BindingDB Entry DOI: 10.7270/Q2M61M6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Bos taurus (Cattle)) | BDBM50316121 (CHEMBL1089229 | N-(3-Benzyl-2-cinnamylthio-4-oxo-3...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University Curated by ChEMBL | Assay Description Inhibition of bovine DHFR after 2 mins | Bioorg Med Chem 18: 2849-63 (2010) Article DOI: 10.1016/j.bmc.2010.03.019 BindingDB Entry DOI: 10.7270/Q2M61M6S | |||||||||||
More data for this Ligand-Target Pair |