Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50438432'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Bos taurus (Cattle))	BDBM50438432 (CHEMBL2414372) Show SMILES S=C(Nc1nc(cs1)-c1n[nH]c(=S)n1-c1ccc(Oc2ccccc2)cc1)Nc1ccccc1 Show InChI InChI=1S/C24H18N6OS3/c32-22(25-16-7-3-1-4-8-16)27-23-26-20(15-34-23)21-28-29-24(33)30(21)17-11-13-19(14-12-17)31-18-9-5-2-6-10-18/h1-15H,(H,29,33)(H2,25,26,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of bovine liver DHFR measured every 1 min for 10 mins				Eur J Med Chem 66: 135-45 (2013) Article DOI: 10.1016/j.ejmech.2013.05.039 BindingDB Entry DOI: 10.7270/Q21C1Z9Q
					More data for this Ligand-Target Pair