Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dimer of Protein farnesyltransferase subunit beta' and Ligand = 'BDBM50117937'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50117937 ((+)4-(2-{4-[9-bromo-4-chloro-1-methyl-(12R)-3,6,7,...) Show SMILES Cc1c[nH]c2c(Cl)cc3CCc4cc(Br)cnc4[C@H](C4CCN(CC4)C(=O)Cc4cc[n+]([O-])cc4)c3c12 Show InChI InChI=1S/C29H28BrClN4O2/c1-17-15-32-29-23(31)14-20-2-3-21-13-22(30)16-33-28(21)27(26(20)25(17)29)19-6-8-34(9-7-19)24(36)12-18-4-10-35(37)11-5-18/h4-5,10-11,13-16,19,27,32H,2-3,6-9,12H2,1H3/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val				J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB
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