Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 1' and Ligand = 'BDBM138508'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138508 (US8877775, 19 | US9073869, 19) Show SMILES CN1C(=O)Cc2cc(ccc12)-c1ccc(C[C@H](NC(=O)[C@H]2NC3CCC2CC3)C#N)cc1 |r,wU:20.21,wD:16.18,(8.68,-3.76,;7.14,-3.76,;6.51,-5.17,;7.28,-6.51,;4.98,-5.01,;4.66,-3.5,;3.33,-2.73,;3.33,-1.19,;4.66,-.42,;5.99,-1.19,;5.99,-2.73,;1.99,-.42,;.66,-1.19,;-.68,-.42,;-.68,1.12,;-2.01,1.89,;-2.01,3.43,;-3.34,4.2,;-4.68,3.43,;-4.68,1.89,;-6.01,4.2,;-7.34,3.43,;-8.68,4.2,;-8.68,5.74,;-7.34,6.51,;-6.01,5.74,;-6.78,4.4,;-7.91,5.53,;-.68,4.2,;.66,4.97,;.66,1.89,;1.99,1.12,)| Show InChI InChI=1S/C26H28N4O2/c1-30-23-11-8-19(13-20(23)14-24(30)31)17-4-2-16(3-5-17)12-22(15-27)29-26(32)25-18-6-9-21(28-25)10-7-18/h2-5,8,11,13,18,21-22,25,28H,6-7,9-10,12,14H2,1H3,(H,29,32)/t18?,21?,22-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	134	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys...				US Patent US9073869 (2015) BindingDB Entry DOI: 10.7270/Q2J9654T
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138508 (US8877775, 19 | US9073869, 19) Show SMILES CN1C(=O)Cc2cc(ccc12)-c1ccc(C[C@H](NC(=O)[C@H]2NC3CCC2CC3)C#N)cc1 |r,wU:20.21,wD:16.18,(8.68,-3.76,;7.14,-3.76,;6.51,-5.17,;7.28,-6.51,;4.98,-5.01,;4.66,-3.5,;3.33,-2.73,;3.33,-1.19,;4.66,-.42,;5.99,-1.19,;5.99,-2.73,;1.99,-.42,;.66,-1.19,;-.68,-.42,;-.68,1.12,;-2.01,1.89,;-2.01,3.43,;-3.34,4.2,;-4.68,3.43,;-4.68,1.89,;-6.01,4.2,;-7.34,3.43,;-8.68,4.2,;-8.68,5.74,;-7.34,6.51,;-6.01,5.74,;-6.78,4.4,;-7.91,5.53,;-.68,4.2,;.66,4.97,;.66,1.89,;1.99,1.12,)| Show InChI InChI=1S/C26H28N4O2/c1-30-23-11-8-19(13-20(23)14-24(30)31)17-4-2-16(3-5-17)12-22(15-27)29-26(32)25-18-6-9-21(28-25)10-7-18/h2-5,8,11,13,18,21-22,25,28H,6-7,9-10,12,14H2,1H3,(H,29,32)/t18?,21?,22-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	134	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2P04,...				US Patent US8877775 (2014) BindingDB Entry DOI: 10.7270/Q20R9N3T
					More data for this Ligand-Target Pair