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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 1' and Ligand = 'BDBM50525300'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 1


(Homo sapiens (Human))		BDBM50525300
PNG
(CHEMBL4447034)
Show SMILES COc1cc(ccc1Nc1ccc(C#C)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(C)CC1
Show InChI InChI=1S/C28H29N5O3/c1-5-20-10-13-26(31-28(20)36-23-9-7-8-21(18-23)29-27(34)6-2)30-24-12-11-22(19-25(24)35-4)33-16-14-32(3)15-17-33/h1,6-13,18-19H,2,14-17H2,3-4H3,(H,29,34)(H,30,31)
PDB

KEGG

UniProtKB/SwissProt

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antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 392n/an/an/an/an/an/a



National Institute of Biological Sciences (NIBS)

Curated by ChEMBL


Assay Description
Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...

J Med Chem 62: 5901-5919 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00631
BindingDB Entry DOI: 10.7270/Q2MG7SX9
More data for this
Ligand-Target Pair