Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17' and Ligand = 'BDBM50313846'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50313846 ((R)-5-(4-fluorophenyl)-5-((5-hydroxy-1-oxoisoindol...) Show SMILES Oc1ccc2C(=O)N(C[C@]3(NC(=O)NC3=O)c3ccc(F)cc3)Cc2c1 |r| Show InChI InChI=1S/C18H14FN3O4/c19-12-3-1-11(2-4-12)18(16(25)20-17(26)21-18)9-22-8-10-7-13(23)5-6-14(10)15(22)24/h1-7,23H,8-9H2,(H2,20,21,25,26)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of TACE by FRET assay				Bioorg Med Chem Lett 20: 1877-80 (2010) Article DOI: 10.1016/j.bmcl.2010.01.148 BindingDB Entry DOI: 10.7270/Q2F76CQ9
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