BindingDB PrimarySearch

Found 3 hits Enz. Inhib. hit(s) with Target = 'Dopamine beta-hydroxylase' and Ligand = 'BDBM50241361'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dopamine beta-hydroxylase (Bos taurus)	BDBM50241361 (CHEMBL1515 \| METHIMAZOLE \| US9138393, Methimazole ...) Show SMILES Cn1cc[nH]c1=S Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	PubMed	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	4.5	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of Dopamine beta hydroxylase at pH 6.6				J Med Chem 29: 2465-72 (1987) BindingDB Entry DOI: 10.7270/Q2BR8R5P
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Bos taurus)	BDBM50241361 (CHEMBL1515 \| METHIMAZOLE \| US9138393, Methimazole ...) Show SMILES Cn1cc[nH]c1=S Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	PubMed	7.16E+5	n/a	n/a	n/a	n/a	n/a	n/a	6.6	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of Dopamine beta hydroxylase at pH 4.5				J Med Chem 29: 2465-72 (1987) BindingDB Entry DOI: 10.7270/Q2BR8R5P
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine beta-hydroxylase (Bos taurus)	BDBM50241361 (CHEMBL1515 \| METHIMAZOLE \| US9138393, Methimazole ...) Show SMILES Cn1cc[nH]c1=S Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	PubMed	n/a	n/a	7.54E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Dopamine beta hydroxylase.				J Med Chem 29: 2465-72 (1987) BindingDB Entry DOI: 10.7270/Q2BR8R5P
TBA Curated by ChEMBL					More data for this Ligand-Target Pair