BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = 'Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C' and Ligand = 'BDBM34651'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM34651 (Amrinon \| Amrinone \| CHEMBL12856 \| Cordemcura \| IN...) Show SMILES Nc1cc(c[nH]c1=O)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibitory activity against PDE1 from cerebral cortex				J Med Chem 40: 3248-53 (1997) Article DOI: 10.1021/jm970089s BindingDB Entry DOI: 10.7270/Q2K93B7D
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM34651 (Amrinon \| Amrinone \| CHEMBL12856 \| Cordemcura \| IN...) Show SMILES Nc1cc(c[nH]c1=O)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration against cGMP PDE I enzyme in guinea pig				J Med Chem 30: 1955-62 (1987) BindingDB Entry DOI: 10.7270/Q27S7MS4
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM34651 (Amrinon \| Amrinone \| CHEMBL12856 \| Cordemcura \| IN...) Show SMILES Nc1cc(c[nH]c1=O)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition cGMP PDE I enzyme				J Med Chem 30: 1963-72 (1987) BindingDB Entry DOI: 10.7270/Q28K79P9
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM34651 (Amrinon \| Amrinone \| CHEMBL12856 \| Cordemcura \| IN...) Show SMILES Nc1cc(c[nH]c1=O)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of guinea pig ventricle				J Med Chem 28: 537-45 (1985) BindingDB Entry DOI: 10.7270/Q2N58MXT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM34651 (Amrinon \| Amrinone \| CHEMBL12856 \| Cordemcura \| IN...) Show SMILES Nc1cc(c[nH]c1=O)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration against cGMP PDE II enzyme in guinea pig				J Med Chem 30: 1955-62 (1987) BindingDB Entry DOI: 10.7270/Q27S7MS4
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human))	BDBM34651 (Amrinon \| Amrinone \| CHEMBL12856 \| Cordemcura \| IN...) Show SMILES Nc1cc(c[nH]c1=O)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of cAMP PDE I enzyme				J Med Chem 30: 1963-72 (1987) BindingDB Entry DOI: 10.7270/Q28K79P9
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair