Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human)) | BDBM168126 (US9073936, 1 | US9598426, 1) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.200 | -56.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
INTRA-CELLULAR THERAPIES, INC. US Patent | Assay Description Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP... | US Patent US9073936 (2015) BindingDB Entry DOI: 10.7270/Q2348J5T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human)) | BDBM168126 (US9073936, 1 | US9598426, 1) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INTRA-CELLULAR THERAPIES, INC. US Patent | Assay Description Assay: The following phosphodiesterase enzymes may be used: 3′,5′-cyclic-nucleotide-specific bovine brain phosphodiesterase (Sigma, St. L... | US Patent US9598426 (2017) BindingDB Entry DOI: 10.7270/Q29S1T2J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human)) | BDBM168126 (US9073936, 1 | US9598426, 1) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1 | -52.2 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
INTRA-CELLULAR THERAPIES, INC. US Patent | Assay Description Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP... | US Patent US9073936 (2015) BindingDB Entry DOI: 10.7270/Q2348J5T | |||||||||||
More data for this Ligand-Target Pair |