Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase TTK' and Ligand = 'BDBM241336'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase TTK (Homo sapiens (Human))	BDBM241336 (US10479788, Example 180 | US11046688, Example 180 ...) Show SMILES COc1cc(ccc1Nc1ncc2cc(C)nc(NCC(C)(C)OC)c2n1)-c1nncn1C Show InChI InChI=1S/C23H28N8O2/c1-14-9-16-11-24-22(29-19(16)20(27-14)25-12-23(2,3)33-6)28-17-8-7-15(10-18(17)32-5)21-30-26-13-31(21)4/h7-11,13H,12H2,1-6H3,(H,25,27)(H,24,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...				US Patent US10479788 (2019) BindingDB Entry DOI: 10.7270/Q2BP055X
					More data for this Ligand-Target Pair
Dual specificity protein kinase TTK (Homo sapiens (Human))	BDBM241336 (US10479788, Example 180 | US11046688, Example 180 ...) Show SMILES COc1cc(ccc1Nc1ncc2cc(C)nc(NCC(C)(C)OC)c2n1)-c1nncn1C Show InChI InChI=1S/C23H28N8O2/c1-14-9-16-11-24-22(29-19(16)20(27-14)25-12-23(2,3)33-6)28-17-8-7-15(10-18(17)32-5)21-30-26-13-31(21)4/h7-11,13H,12H2,1-6H3,(H,25,27)(H,24,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.0	25
Cancer Research Technology Limited US Patent					Assay Description The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...				US Patent US9409907 (2016) BindingDB Entry DOI: 10.7270/Q2C24VB2
					More data for this Ligand-Target Pair