Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1A' and Ligand = 'BDBM293479'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM293479 (US10106527, Compound 93 | US10544128, Compound 93 ...) Show SMILES CN1CCC2(CN(C2)c2cc(ccn2)C(=O)Nc2cc3cc(ccc3cn2)-c2cnn(C)c2)CC1 Show InChI InChI=1S/C27H29N7O/c1-32-9-6-27(7-10-32)17-34(18-27)25-13-20(5-8-28-25)26(35)31-24-12-22-11-19(3-4-21(22)14-29-24)23-15-30-33(2)16-23/h3-5,8,11-16H,6-7,9-10,17-18H2,1-2H3,(H,29,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	25
Samumed, LLC US Patent					Assay Description Briefly, recombinant DYRK1A kinase, ATP and Ser/Thr peptide 18 were prepared in 1× Kinase buffer to final concentrations of 0.19 μg/mL, 30 μ...				US Patent US10106527 (2018) BindingDB Entry DOI: 10.7270/Q2PN97Q3
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM293479 (US10106527, Compound 93 | US10544128, Compound 93 ...) Show SMILES CN1CCC2(CN(C2)c2cc(ccn2)C(=O)Nc2cc3cc(ccc3cn2)-c2cnn(C)c2)CC1 Show InChI InChI=1S/C27H29N7O/c1-32-9-6-27(7-10-32)17-34(18-27)25-13-20(5-8-28-25)26(35)31-24-12-22-11-19(3-4-21(22)14-29-24)23-15-30-33(2)16-23/h3-5,8,11-16H,6-7,9-10,17-18H2,1-2H3,(H,29,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The DYRKIA kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies-a Divis...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM293479 (US10106527, Compound 93 | US10544128, Compound 93 ...) Show SMILES CN1CCC2(CN(C2)c2cc(ccn2)C(=O)Nc2cc3cc(ccc3cn2)-c2cnn(C)c2)CC1 Show InChI InChI=1S/C27H29N7O/c1-32-9-6-27(7-10-32)17-34(18-27)25-13-20(5-8-28-25)26(35)31-24-12-22-11-19(3-4-21(22)14-29-24)23-15-30-33(2)16-23/h3-5,8,11-16H,6-7,9-10,17-18H2,1-2H3,(H,29,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1QR6
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM293479 (US10106527, Compound 93 | US10544128, Compound 93 ...) Show SMILES CN1CCC2(CN(C2)c2cc(ccn2)C(=O)Nc2cc3cc(ccc3cn2)-c2cnn(C)c2)CC1 Show InChI InChI=1S/C27H29N7O/c1-32-9-6-27(7-10-32)17-34(18-27)25-13-20(5-8-28-25)26(35)31-24-12-22-11-19(3-4-21(22)14-29-24)23-15-30-33(2)16-23/h3-5,8,11-16H,6-7,9-10,17-18H2,1-2H3,(H,29,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	n/a
TBA					Assay Description The DYRKIA kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				Citation and Details BindingDB Entry DOI: 10.7270/Q2JW8JR2
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM293479 (US10106527, Compound 93 | US10544128, Compound 93 ...) Show SMILES CN1CCC2(CN(C2)c2cc(ccn2)C(=O)Nc2cc3cc(ccc3cn2)-c2cnn(C)c2)CC1 Show InChI InChI=1S/C27H29N7O/c1-32-9-6-27(7-10-32)17-34(18-27)25-13-20(5-8-28-25)26(35)31-24-12-22-11-19(3-4-21(22)14-29-24)23-15-30-33(2)16-23/h3-5,8,11-16H,6-7,9-10,17-18H2,1-2H3,(H,29,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRKIA kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair