Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50041076'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50041076 (CHEMBL3355419) Show SMILES Fc1c(Cl)cccc1[C@H]1[C@@H](NC2(CCC2)[C@]11C(=O)Nc2cc(Cl)ccc12)C(=O)NCCN1CCOCC1 |r| Show InChI InChI=1S/C27H29Cl2FN4O3/c28-16-5-6-18-20(15-16)32-25(36)27(18)21(17-3-1-4-19(29)22(17)30)23(33-26(27)7-2-8-26)24(35)31-9-10-34-11-13-37-14-12-34/h1,3-6,15,21,23,33H,2,7-14H2,(H,31,35)(H,32,36)/t21-,23+,27-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine Curated by ChEMBL					Assay Description Binding affinity to human His-tagged MDM2 (1 to 118 residues) using FAM tagged p53-based peptide by fluorescence prolarization based protein binding ...				J Med Chem 57: 10486-98 (2014) Article DOI: 10.1021/jm501541j BindingDB Entry DOI: 10.7270/Q2HH6MQK
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50041076 (CHEMBL3355419) Show SMILES Fc1c(Cl)cccc1[C@H]1[C@@H](NC2(CCC2)[C@]11C(=O)Nc2cc(Cl)ccc12)C(=O)NCCN1CCOCC1 |r| Show InChI InChI=1S/C27H29Cl2FN4O3/c28-16-5-6-18-20(15-16)32-25(36)27(18)21(17-3-1-4-19(29)22(17)30)23(33-26(27)7-2-8-26)24(35)31-9-10-34-11-13-37-14-12-34/h1,3-6,15,21,23,33H,2,7-14H2,(H,31,35)(H,32,36)/t21-,23+,27-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine Curated by ChEMBL					Assay Description Binding affinity to human His-tagged MDM2 (1 to 118 residues) using FAM tagged p53-based peptide by fluorescence prolarization based protein binding ...				J Med Chem 57: 10486-98 (2014) Article DOI: 10.1021/jm501541j BindingDB Entry DOI: 10.7270/Q2HH6MQK
					More data for this Ligand-Target Pair