Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'EF-hand calcium-binding domain-containing protein 4B' and Ligand = 'BDBM141409'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EF-hand calcium-binding domain-containing protein 4B (Homo sapiens (Human))	BDBM141409 (US10668051, Compound Example 49 | US8921364, 49) Show SMILES FC(F)(F)c1cc(C2CC2)n(n1)-c1ccc(NC(=O)c2c(Cl)cncc2Cl)cc1 Show InChI InChI=1S/C19H13Cl2F3N4O/c20-13-8-25-9-14(21)17(13)18(29)26-11-3-5-12(6-4-11)28-15(10-1-2-10)7-16(27-28)19(22,23)24/h3-10H,1-2H2,(H,26,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	65.5	n/a	n/a	n/a	n/a	n/a	37
Rhizen Pharmaceuticals SA US Patent					Assay Description Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat # T9033) induced endoplasmic calcium release in Jurkat cells. (see Yasu...				US Patent US8921364 (2014) BindingDB Entry DOI: 10.7270/Q2N58K3N
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