BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelin receptor type B' and Ligand = 'BDBM50291486'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelin receptor type B


(Homo sapiens (Human))		BDBM50291486
PNG
(2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-ethyl]-thiop...)
Show SMILES Cc1noc(NS(=O)(=O)c2ccsc2CCc2cc3OCOc3cc2C)c1Br
Show InChI InChI=1S/C18H17BrN2O5S2/c1-10-7-13-14(25-9-24-13)8-12(10)3-4-15-16(5-6-27-15)28(22,23)21-18-17(19)11(2)20-26-18/h5-8,21H,3-4,9H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
n/an/a 8.90E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assay

Bioorg Med Chem Lett 7: 939-944 (1997)


Article DOI: 10.1016/S0960-894X(97)00133-9
BindingDB Entry DOI: 10.7270/Q2959HKC
More data for this
Ligand-Target Pair