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Found 1 hit Enz. Inhib. hit(s) with Target = 'Ephrin type-B receptor 4' and Ligand = 'BDBM50195883'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ephrin type-B receptor 4


(Homo sapiens (Human))		BDBM50195883
PNG
(7-bromo-3-(3-chloro-4-fluorophenyl)thieno[3,2-c]py...)
Show SMILES Nc1ncc(Br)c2scc(-c3ccc(F)c(Cl)c3)c12
Show InChI InChI=1S/C13H7BrClFN2S/c14-8-4-18-13(17)11-7(5-19-12(8)11)6-1-2-10(16)9(15)3-6/h1-5H,(H2,17,18)
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GlaxoSmithKline K.K.

Curated by ChEMBL


Assay Description
Inhibition of human EphB4 by scintillation proximity method

Bioorg Med Chem Lett 17: 250-4 (2006)


Article DOI: 10.1016/j.bmcl.2006.09.050
BindingDB Entry DOI: 10.7270/Q2SB45D5
More data for this
Ligand-Target Pair