Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM133710'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM133710 (US8846699, 26) Show SMILES Fc1cc(Br)ccc1Nc1ncnc2cc(OCCNC(=O)C=C)c(NC(=O)C=C)cc12 Show InChI InChI=1S/C22H19BrFN5O3/c1-3-20(30)25-7-8-32-19-11-17-14(10-18(19)28-21(31)4-2)22(27-12-26-17)29-16-6-5-13(23)9-15(16)24/h3-6,9-12H,1-2,7-8H2,(H,25,30)(H,28,31)(H,26,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	25
Hanmi Pharm. Co., Ltd. US Patent					Assay Description EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...				US Patent US8846699 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DRK
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