Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Eukaryotic translation initiation factor 2-alpha kinase 1' and Ligand = 'BDBM50414891'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 2-alpha kinase 1 (Homo sapiens (Human))	BDBM50414891 (CHEMBL574005) Show SMILES COc1cc-2c(Cc3c(NCc4c(Cl)cccc4Cl)[nH]nc-23)cc1OCC(O)CO Show InChI InChI=1S/C21H21Cl2N3O4/c1-29-18-7-13-11(6-19(18)30-10-12(28)9-27)5-14-20(13)25-26-21(14)24-8-15-16(22)3-2-4-17(15)23/h2-4,6-7,12,27-28H,5,8-10H2,1H3,(H2,24,25,26)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human HRI kinase				Bioorg Med Chem Lett 19: 6548-51 (2009) Article DOI: 10.1016/j.bmcl.2009.10.033 BindingDB Entry DOI: 10.7270/Q26Q1ZGZ
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