Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'F420-dependent glucose-6-phosphate dehydrogenase [W44Y]' and Ligand = 'BDBM197174'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
F420-dependent glucose-6-phosphate dehydrogenase [W44Y] (Mycobacterium tuberculosis)	BDBM197174 (Glucose-6-phosphate (G6P)) Show SMILES O[C@H](COP(O)(O)=O)[C@H](O)[C@H](O)[C@@H](O)C=O Show InChI InChI=1S/C6H13O9P/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14/h1,3-6,8-11H,2H2,(H2,12,13,14)/t3-,4+,5+,6-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	DrugBank KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.90E+4	n/a	n/a	n/a	7.0	n/a
The University of Texas at Arlington					Assay Description Fluorescence spectroscopy was used to determine the G6P and F420 dissociationconstants (Kd) for the FGD wild-type and mutant enzymes. A Spectrosil Qu...				Biochemistry 55: 5566-5577 (2016) Article DOI: 10.1021/acs.biochem.6b00638 BindingDB Entry DOI: 10.7270/Q2C8284N
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