BindingDB PrimarySearch

Found 3 hits Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' and Ligand = 'BDBM50426435'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Fatty acid synthase (Homo sapiens (Human))	BDBM50426435 (CHEMBL2322370) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
3-V Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human FASN assessed as release of co-enzyme A				ACS Med Chem Lett 4: 113-7 (2013) Article DOI: 10.1021/ml300335r BindingDB Entry DOI: 10.7270/Q2P84D76
3-V Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty acid synthase (Homo sapiens (Human))	BDBM50426435 (CHEMBL2322370) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
3-V Biosciences, Inc. US Patent					Assay Description The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...				US Patent US8871790 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QD3
3-V Biosciences, Inc. US Patent					More data for this Ligand-Target Pair
Fatty acid synthase (Rattus norvegicus)	BDBM50426435 (CHEMBL2322370) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
3-V Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of rat FASN assessed as release of co-enzyme A				ACS Med Chem Lett 4: 113-7 (2013) Article DOI: 10.1021/ml300335r BindingDB Entry DOI: 10.7270/Q2P84D76
3-V Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair