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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM6157'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM6157
PNG
(1,6-naphthyridine 26 | 3-tert-butyl-1-(7-{[5-(diet...)
Show SMILES CCN(CC)CCCCCNc1cc2nc(NC(=O)NC(C)(C)C)c(cc2cn1)-c1cc(OC)cc(OC)c1
Show InChI InChI=1S/C30H44N6O3/c1-8-36(9-2)14-12-10-11-13-31-27-19-26-22(20-32-27)17-25(21-15-23(38-6)18-24(16-21)39-7)28(33-26)34-29(37)35-30(3,4)5/h15-20H,8-14H2,1-7H3,(H,31,32)(H2,33,34,35,37)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 28n/an/an/an/an/an/a



University of Auckland



Assay Description
Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...


J Med Chem 48: 4628-53 (2005)


Article DOI: 10.1021/jm0500931
BindingDB Entry DOI: 10.7270/Q2DV1H3W
More data for this
Ligand-Target Pair